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下面列出的参考读物是本课程的基础。点击题目链接可以看到文章的摘要。
参考读物清单
Abrisquita-Gomez, et al. "Recognition memory for emotional pictures in Alzheimer's patients.（题目：阿尔兹海默氏征患者的情感认知记忆）" Acta Neurologica Scandinavica 105 (2002): 51-54.
Baddeley, A. D., S. Bressi, S. Della Sala, R. Logie, and H. Spinnler. "The decline of working memory in Alzheimer's disease（题目：阿尔兹海默氏征患者工作记忆的衰退）." Brain 114 (1991): 2521-2542.
Baddeley, A. D. "Working memory（题目：工作记忆）." Science 255 (1992): 556-559.
Craik, F. I. M., and J. McDowd. "Age differences in recall and recognition.（题目：记忆与认知的年龄差异）" Journal of Experimental Psychology: Learning, Memory and Cognition 13(3) (1987): 474-479.
Glenner, G. G. "Amyloid ? protein and the basis for Alzheimer's disease（题目：淀粉样β蛋白与阿尔兹海默氏征的病理基础）." Prog Clin Biol Res. 317 (1989): 857-68.
Glenner, G. G., and C. W. Wong. "Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein（题目：阿尔兹海默氏征与唐氏综合征的共性：独特的脑血管淀粉样纤维蛋白）." Biochem Biophys Res Commun. 122(3) (1984): 1131-5.
Glisky, E., et al. "Source memory in older adults: An encoding or retrieval problem?（题目：老年人群中的源记忆：编码问题还是修复问题？）" Journal of Experimental Psychology: Learning, Memory and Cognition 27(5) (2001): 1131-1146.
Hamann, et al. "Impaired fear conditioning in Alzheimer's disease（题目：在阿尔兹海默氏征中受损的恐惧条件反射）." Neuropsychologia 40 (2002): 1187-1195.
Head, D., N. Raz, F. Gunning-Dizxon, A. Williamson, and J. D. Acker. "Age-related differences in the course or cognitive skill acquisition: the role of regional cortical shrinkage and cognitive resources（题目：在获得认识能力过程中不同年龄的区别：认知源和区域性皮层皱缩的作用）." Psychology and Aging 17 (2002): 72-84.
Irizarry, C., and B. Hyman. "Alzheimer disease therapeutics（题目：阿尔兹海默氏病的治疗）." Journal of Neuropathology and Experimental Neurology 60(10) (2001): 923-928.
Jonides, J., C. Marshuetz, E. E. Smith, E. E. Reuter-Lorenz, and A. Hartley. "Age differences in behavior and PET activation reveal differences in interference resolution in verbal working memory（题目：在行为学以及正电子发射断层扫描中被激活区域上的年龄差别，揭示了在言语工作记忆中干涉的区分？）." Journal of Cognitive Neuroscience 12 (2000): 188-196.
Kensinger, E., and S. Corkin. "Cognition in aging and age-related disease.（题目：衰老以及与年龄相关疾病的认知行为）" In Encyclopedia of Neuroscience. Edited by G. Adelman. （印刷中）.
------. "Alzheimer disease.（题目：阿尔兹海默氏征）" In Encylcopedia of Cognitive Science. Edited by L. Nadel. UK: Nature Publishing Group, 2003, 83-89.
------. "Neural changes in aging.（题目：衰老的神经学改变）" In Encylcopedia of Cognitive Science. Edited by L. Nadel. UK: Nature Publishing Group, 2003, 70-78.
Kensinger, E. A., D. K. Shearer, J. J. Locascio, J. H. Growdon, and S. Corkin. "Working memory in mild Alzheimer's disease and early Parkinson's disease（题目：早期帕金森氏症和中期阿尔兹海默氏征的工作记忆）." Neuropsychology. (in press).
Naveh-Benjamin, M. "Adult age differences in memory performance: Tests of an associative deficit analysis（题目：成年人记忆行为的年龄差别：联想缺陷分析测验）." Journal of Experimental Psychology: Learning, Memory and Cognition 26(5) (2000): 1170-1187.
Reuter-Lorenz, P. "New visions of the aging mind and brain（题目：智力和脑老化的新观点）." Trends in Cognitive Sciences 6(9) (2002): 394-400.
Rypma, B., V. Prabhakaran, J. E. Desmond, and J. D. Gabrieli. "Age differences in prefrontal cortical activity in working memory（题目：在工作记忆中额叶前皮层行为的年龄差别）." Psychology and Aging 16 (2001): 371-384.
Salthouse, T. "The aging of working memory(题目：工作记忆的老化)." Neuropsychology 8 (1994): 535-543.
Selkoe. "Part 1: Causes; Current Treatments(题目：第一部分：发病原因，当前的治疗)." 545-552
Selkoe. "Part 2: Inhibition of ?-Secretase（题目：第二部分：?分泌酶的抑制）." 552-556.
Selkoe, D. J., and D. Schenk. "Alzheimer's Disease: Molecular Understanding predicts Amyloid-based Therapeutics.（题目：阿尔兹海默氏征：针对淀粉样蛋白治疗的分子基础）" Annu Rev Pharmacol Toxicol. 43(2003): 545-84.
Tessitore, et al. "Dopamine modulates the response of the human amygdala: a study in Parkinson's disease（题目：人扁桃体的多巴胺调节反应：帕金森氏症研究）." Journal of Neuroscience 22(20) (1991): 9099-9103.
请为下列文章写出简短的大纲:
Bard, F., C. Cannon, R. Barbour, R. L. Burke, D. Games, H. Grajeda, T. Guido, K. Hu, J. Huang, et al. "Peripherally administered antibodies against amyloid ?-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease(题目：阿尔兹海默氏征模型小鼠外周给予β样淀粉蛋白的抗体，药物能够进入中枢神经系统并减少模型小鼠的病理学特征)." Nat Med 6(8) (2000): 916-9.
Blanchard, B. J., A. E. Hiniker, C. C. Lu, Y. Margolin, A. S. Yu, and V. M. Ingram. "Elimination of Amyloid ? Neurotoxicity(题目：β样淀粉蛋白神经毒性的消减)." J Alzheimers Dis. 2(2) (2000): 137-149.
Blanchard, B. J., G. Konopka, M. Russell, and V. M. Ingram. "Mechanism and prevention of neurotoxicity caused by ?-amyloid peptides: relation to Alzheimer's disease(题目：关于阿尔兹海默氏征：β样淀粉蛋白引起神经毒性的机制与预防)." Brain Res. 776(1-2) (1997): 40-50.
Citron, M., T. Oltersdorf, C. Haass, L. McConlogue, A. Y. Hung, P. Seubert, C. Vigo-Pelfrey, I. Lieberburg, and D. J. Selkoe. "Mutation of the ?-amyloid precursor protein in familial Alzheimer's disease increases ?-protein production(题目：β样淀粉蛋白的前体蛋白突变导致了家族性阿尔兹海默氏征患者β样淀粉蛋白的增生)." Nature 360(6405) (1992): 672-4.
Hartley, D. M., D. M. Walsh, C. P. Ye, T. Diehl, S. Vasquez, P. M. Vassilev, D. B. Teplow, and D. J. Selkoe. "Protofibrillar intermediates of amyloid ? -protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons(题目：β样淀粉蛋白的初纤维的中间体诱导了电生理学急剧改变和皮层神经元的渐进性毒性。)." J Neurosci 19(20) (1999): 8876-84.
Morgan, D., et al. "A ? peptide vaccination prevents memory loss in an animal model of Alzheimer's disease(题目：在阿尔兹海默氏征疾病的动物模型上β样淀粉蛋白的疫苗可以阻断记忆的丧失)." Nature 408(6815) (2000): 982-5.
Schenk, D., et al. "Immunization with amyloid-? attenuates Alzheimerdisease- like pathology in the PDAPP mouse(题目：在PDAPP模型鼠上β样淀粉蛋白的免疫疗法可以削弱其病理学表征)." Nature 400(6740) (1999): 173-7.
Selkoe. "Part 3: Inhibition of ?-Secretase(题目：第三部分：γ分泌酶的抑制)." 556-564.
Selkoe. "Part 4: Immunological Approach to Therapy." 564-571.
Selkoe. "Part 5: Other Approaches to Therapy(题目：第五部分：治疗阿尔兹海默氏征的其它方法)." 571-576.
Sherrington, R., E. I. Rogaev, Y. Liang, E. A. Rogaeva, G. Levesque, M. Ikeda, H. Chi, C. Lin, G. Li, K. Holman, et al. "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease(题目：一个早发家族性阿尔兹海默氏征突变基因的克隆)." Nature 375(6534) (1995 ): 754-60.
Walsh, D. M., I. Klyubin, J. V. Fadeeva, W. K. Cullen, R. Anwyl, M. S. Wolfe, M. J. Rowan, and D. J. Selkoe. "Naturally secreted oligomers of amyloid ? protein potently inhibit hippocampal long-term potentiation in vivo（题目：体内正常分泌的淀粉样蛋白寡聚体，对海马长时程增强有较强的抑制）." Nature 416(6880) (2002): 535-9.
Yan, R., P. Han, H. Miao, P. Greengard, and H. Xu. "The transmembrane domain of the Alzheimer's ?-secretase (BACE1) determines its late Golgi localization and access to ?-amyloid precursor protein (APP) substrate（题目：阿尔兹海默氏征的β分泌酶的穿膜结构域，决定了晚期其在高尔基体的定位并逐步接近其底物—前体蛋白APP）." J Biol Chem. 276(39) (2001) : 36788-96.
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