Crystal structure of shikimate kinase. (Image courtesy of the RCSB PDB
. PDB ID: 1VIA. Badger, J., et al. "Structural analysis of a set of proteins resulting from a bacterial genomics project." Proteins
60 (2005): 787-796.)
This course features a full set of problem sets with solutions in the assignments
5.451 is a half-semester introduction to natural product biosynthetic pathways. The course covers the assembly of complex polyketide, peptide, terpene and alkaloid structures. Discussion topics include chemical and biochemical strategies used to elucidate natural product pathways.